Latest Biotech News


EU – RENEWED EFFORTS TO PROCESS GM APPROVALS

EU Commission renews bid to unblock GMO crop approvals

6 November, 2013 Source: Reuters

www.chicagotribune.com/business/sns-rt-us-eu-gmo-cultivation-20131106,0,7859830.story

 BRUSSELS (Reuters) – The European Commission proposed on Wednesday that governments approve only the third ever genetically modified crop for cultivation in Europe, but took steps to avert an expected backlash from France and other GMO opponents.

The proposal covers an insect-resistant maize developed jointly by DuPont and Dow Chemical which, if approved, would end Monsanto’s current monopoly in Europe’s tiny market for GMO crops.

The Commission said it was “duty bound” to make the proposal after Europe’s second-highest court in September censured the EU executive for lengthy delays in the approval process, first launched back in 2001.

EU governments now have three months to vote on the issue. The plan is likely to face strong opposition from France, as well as Austria, Italy and other countries that have previously banned the growing of GMO crops.

But with Britain, Spain and Sweden expected to back the proposal, there may be little that opponents can do to prevent approval.

Under EU rules applying to the application, the Commission is obliged to approve cultivation unless a weighted majority of governments vote against it.

Seeking to head off criticism from anti-GMO governments and campaigners, the Commission called for the restart of stalled talks on draft EU rules to allow member states to decide individually whether to ban or restrict GMO cultivation.

That would enable countries to prevent farmers from growing GMO crops even if they had been approved for cultivation at EU level, provided they do not use environmental or health reasons to justify the restrictions.

EU health commissioner Tonio Borg said he hoped the draft legislation would be discussed at the next meeting of EU environment ministers in December, but EU officials said the issue was not currently on the meeting agenda.

Borg also hinted that Wednesday’s move would not lead to a rush of similar cultivation approval proposals from the Commission, despite a backlog of six applications currently awaiting a decision.

“I know that this is a controversial subject, and that therefore one does not rush into areas where angels fear to tread,” he told a news briefing in Brussels.

BACKGROUND

Only two GMO crops are currently approved for cultivation in the European Union. Monsanto’s insect-resistant maize – known as MON810 – is the only one grown commercially, and was sown on around 130,000 hectares in 2012, mostly in Spain.

That compares with about 100 GMO varieties approved elsewhere in the world, with global cultivation estimated to cover some 170 million hectares in 2012.

The maize variety covered by Wednesday’s proposal is known as 1507, and is sold outside Europe under the Herculex brand name. Like MON810, the plant has been modified to produce its own insecticide against the European corn borer.

If the product is approved it is unlikely to lead to an overall expansion in GMO cultivation in Europe but could challenge sales of MON810, particularly in Europe’s biggest market Spain.

Since the cultivation request was first lodged in 2001, the EU’s food safety watchdog EFSA has delivered six positive scientific safety assessments on 1507.

… In a separate decision on Wednesday, the Commission granted import approval for three GMO maize varieties for use in food and feed after EU governments failed to reach a decision.

 


USA – AMERICANS PAY LITTLE ATTENTION TO GM

Most Americans pay little attention to genetically modified foods, survey says

4 November, 2013

Source: http://phys.org/news/2013-11-americans-attention-genetically-foods-survey.html – jCp

The survey, released by researchers at Rutgers University, found that more than half (53 per cent) say they know very little or nothing at all about genetically modified (GM) foods, and one in four (25 per cent) say they have never heard of them. Even with the media attention resulting from recent ballot initiatives in California (Proposition 37) and Washington State (Initiative 522) and legislative actions in at least 20 other states that would require labeling of GM foods, the Rutgers study found that only about a quarter (26 per cent) of Americans realize that current regulations do not require GM products to be labeled.

“Americans do care about what’s in their food, and they do read labels,” said William Hallman, professor of human ecology in Rutgers’ School of Environmental and Biological Sciences, and lead author of the study.

“Eighty-two percent of the respondents told us they sometimes or frequently or always read food labels. But determining what labeling information they value is not a straightforward task. Whether consumers say they want GM food labels depends on how you ask the question, so we asked about it in several ways.”

Before introducing the idea of GM foods, the survey participants were asked simply “What information would you like to see on food labels that is not already on there?” In response, only seven per cent raised GM food labeling on their own. A similar number (six per cent) said they wanted more information about where the food product was grown or processed. In contrast, when asked directly whether GM foods should be required to be labeled, 73 per cent said yes.

The survey asked respondents to rate the importance of various kinds of information on food labels. Fifty-nine per cent said that it was very or extremely important to have information about whether the product contains GM ingredients on a label. This is about the same number who indicated that it was similarly important to have information about whether the product was grown using hormones (63 per cent), pesticides (62 per cent), or antibiotics (61 per cent), whether it was grown or raised in the United States (60 per cent), and whether the product contains allergens (59 per cent).

The respondents were part of a nationally representative Internet-based panel, and the data reported here have been weighted to be nationally representative, with a +/- three per cent margin of error. A summary of the study’s findings is available online at humeco.rutgers.edu/documents_PDF/news/GMlabelingperceptions.pdf . The study authors are Hallman, Cara L. Cuite, and Xenia K. Morin, all of the School of Environmental and Biological Sciences.


AUS - GM CROP BAN IN SA UNTIL 2019

Genetically modified crops ban to be extended in South Australia

7 November 2013

Source: www.abc.net.au/news/2013-11-07/gm-crops-ban-fruit-fly-research-sterile-males-qflies/5075206

South Australia will extend a moratorium on genetically modified crops until at least 2019.

SA is the only mainland state maintaining a ban on GM crop production and trials.

Government Minister Leon Bignell said the state’s GM-free status gave primary producers a competitive advantage in key overseas markets, including Japan.

He said a continuing ban would help protect premium food and wine production and allow grain producers to attract higher prices.

“We’ve got a strong reputation not just around Australia but around the world for producing clean, green premium food and we think having a moratorium on the growing of GM crops really helps us in that end,” he said.

“People are paying a $50 a tonne premium and we think there’s a lot more advantages to having the moratorium in place than to lift it.”

The Opposition said it too would ensure there was a ban on genetically modified crops until at least 2019 if it took office next March.

But Opposition agriculture spokesman David Ridgway said a ban needed regular review to ensure restrictions on growing GM crops did not put local farmers at a disadvantage.

“We support a moratorium but it needs to be monitored,” he said.

“The Government claims that we get benefits, more dollars per tonne, it enhances our reputation – it should be continually monitored just to make sure our farmers and our producers are getting the benefits the Government claims that we are getting a market advantage for our quality food and wine.”


BANGLADESH – GM EGGPLANT

MODIFIED BRINJAL FINALLY SEES THE LIGHT

 

Source: http://www.thedailystar.net/beta2/news/modified-brinjal-finally-sees-light/

The National Committee on Biosafety (NCB) yesterday officially released the country’s first genetically modified (GM) food crop, brinjal, which is infused with pest-resistant gene.

The decision was taken following a two-day meeting of the NCB, the highest regulatory body for GM crop release, held at the environment ministry with its secretary in the chair.
With this decision, Bangladesh becomes the 29th country in the world to grow GM crop. In South Asia, India, Pakistan and Myanmar grow GM crop cotton. With the NCB nod, Bangladesh becomes the first in the region to grow a GM food crop.

Scientists at the Bangladesh Agricultural Research Institute (Bari) genetically engineered brinjal, one of the most consumed vegetables in the country, by inserting a crystal protein gene (Cry1Ac) taken from the soil bacterium Bacillus thuringiensis, otherwise known as Bt. Since then it has been known as Bt Brinjal.
The Bt gene insertion in brinjal gives it resistance against fruit and shoot borer (FSB), considered to be the most widespread and devastating pest in South and Southeast Asia. FSB infestations inflict 50 to 70 percent yearly crop loss in brinjal.

 

 

 


USA - GM GRAPE BLOG

Happy Hour: Why Genetically Engineered Grapes Would Make Great Wine

Source: http://www.gizmodo.com.au/2013/10/why-genetically-engineered-grapes-would-make-great-wine/

I am 99.9 per cent sure that there will never be commercial production of genetically engineered wine grapes (“GMO” to use the common misnomer). Even so, I’d like to indulge in imagining what could be if we lived in some parallel universe where rational scientific thinking prevailed.

Wine grapes are an extremely logical crop for genetic engineering because there is no tolerance for changing varieties. For annual crops like grains or vegetables, new varieties are bred on a regular basis to solve pest issues or to improve features like taste or shelf life. Breeding of perennial fruit crops is a much, much slower process, but entirely new varieties are still introduced from time to time (e.g. Jazz or Pink Lady apples). Even what we call “heirloom varieties” of most vegetable or fruit crops are mostly quite young by wine grape standards.

 

Conventional breeding just isn’t a viable option for wine grapes, not because it couldn’t be done, but because in an industry so focused on quality and tradition, no one would consider it. The wine industry is based on specific varieties which are hundreds of years old and for which no new variety would ever be acceptable. That is true for varieties in their original appellations (e.g. Pinot Noir and Chardonnay in Burgundy or Cabernet Sauvignon and its blending partners in Bordeaux). It is also true for those same varieties that now make great wines in “New World” (e.g. Malbec in Argentina, Zinfandel in California, or Syrah in Australia).

Therefore, wine grape varieties have been cloned for hundreds of years, specifically to avoid any genetic change (they have always been grown from rooted cuttings or from grafted buds). Grapes make seeds, but the seed won’t grow up to be the same variety as the parent, thus they are never used as a way to grow new vines.

The Downside of Ancient Varieties

Of course, by sticking to very old varieties, wine grape growers must deal with many problems which might otherwise have been solved through breeding. Grape growers have been able to deal with some pests that attack the roots by grafting onto diverse “root stocks” with novel genetics. But rootstocks can only help with a limited number of grape growing challenges.

Why Genetic Engineering Would Be Logical For Grapes

Biotechnology is a perfect solution for wine grape issues because it allows changes to address one specific problem without disrupting any of the characteristics that determine quality. Of course, each variety would have to be individually transformed, but in our imaginary rational universe the regulatory regime would be made easier for multiple uses of the same basic genetic construct.

So, genetic engineering could be a very cool solution for various challenges for grapes. I’ll list a few of the diseases that might be fixable this way.

  • Mildews – Downy Mildew, Powdery Mildew
  • Rot Reduction – Botrytis Bunch Rot
  • Viral Diseases – Leafroll Virus
  • Pierce’s Disease – A Potentially Existential Threat

Voluntary “GMO labelling” Would Be Easy for Wine

Because wine grapes can be extremely valuable (e.g. as much as $US10-20,000/acre), and because quality is closely connected with the location where they are grown, “identity preservation” is common in the industry. It would be entirely feasible for grapes which were or were not “GMO” to be kept separate to what ever extent was desired. So, one winery could proudly label their wine as “improved via biotechnology to provide disease resistance,” while the neighbouring winery could confidently claim not to be “non-GMO” if they so desired. Again, remember I’m talking about what could happen in a parallel universe where reason prevails. In our universe reason quickly yielded to the politics of fear and unfounded concerns about “genetic contamination.”

So, there will probably never be commercial “GMO grapes” in our universe, but that doesn’t change the fact that it is a cool concept.

Pictures: Shutterstock/William J. Mahnken, Colorado Chardonnay SDSavage, University of Georgia Photo Archive, Wikipedia, Rotting Chardonnay SDSavage, Naotake Murayama, Oklahoma State University

 


USA – GM ORANGE TREES BEING TESTED

GM virus-resistant citrus trees move to field trials

Source: http://www.thegrower.com/news/citrus-greening/121663929.html

The most effective method of controlling the devastating citrus greening disease that has ravaged Florida’s orange groves also may be the most controversial.

A report from the National Academy of Sciences says the most powerful long-time management tool for the bacterium that causes the disease and, possibly, for the Asian citrus psyllid that spreads it, may be genetic engineering.

“Genetic engineering, in the form of transgenic citrus or citrus inoculated with a transgene-expressing virus vector, holds the greatest hope for generating citrus cultivars resistant to (the causal bacterium and the psyllid),” the report says.

 

At the same time, the report warns that groups opposed to genetically modified foods of any kind may try to dissuade the public from turning to genetically engineered orange juice.

Meantime, efforts continue toward finding a solution to citrus greening, also called huanglongbing—or HLB—which now is present in nearly all of Florida’s citrusproducing counties but is most prevalent in the southern areas of the state.

The state’s citrus industry is well worth preserving.

“There would be great repercussions for Florida’s economy if the estimated $9.3 billion annual economic benefit of the citrus industry were to be lost or significantly diminished,” the NAS report says.

T. Erik Mirkov, professor of plant virology at Texas A&M University in College Station, has been at the forefront of the search for a genetic solution to greening disease and appears to be making progress.

“We’ve found some genes in spinach that we’ve transferred into citrus that provide resistance,” he says.

Mirkov has received a permit from the U.S. Department of Agriculture to conduct field testing of trees in Florida.

“We’ve got good results in the greenhouse, and now we’re making sure it holds up in the field,” he says.

Although Mirkov’s work appears promising, he still has a way to go. “We don’t have what I would call immunity quite yet,” he says.


TAS - POPPY GROWERS WANT GM BAN LIFTED

LEGAL CHALLENGE THREAT OVER GMO MORATORIUM

13 Oct 2013

www.abc.net.au/news/2013-10-13/legal-challenge-threat-over-gmo-moratorium/5019080

Tasmanian poppy growers say they will consider a legal challenge if the State Government refuses to allow genetically modified poppies.

The Government’s moratorium on genetically modified crops expires next year.

Yesterday, more than 100 protesters marched through Hobart, demanding the Government continue its ban on GM crops.

Despite a Government review underway, the Premier Lara Giddings wants the ban to remain.

“We do not believe that we should have GM products grown here in Tasmania,” she said.

The Deputy Liberal leader Jeremy Rockliff also says his party is yet to be convinced of the need for a change.

The Poppy Growers Association’s Glynn Williams says if the ban is not revoked, poppy growers could mount a legal action.

“We’re very confident that there are good grounds to challenge a refusal of the permit to grow GM poppies in Tasmania,” she said.

Mr Williams says genetically modified poppies would not affect Tasmania’s food or honey production.


USA – AG COEXISTENCE INPUT SOUGHT

USDA Announces Request for Public Input on Agricultural Coexistence Acts on Recommendations Made by Advisory Committee on Biotechnology in 21st Century

20 September, 2013. Source: US Department of Agriculture

www.usda.gov/wps/portal/usda/usdahome?contentid=AC21Main.xml&contentidon ly=true.

Agriculture Secretary Tom Vilsack announced today that the Department of Agriculture (USDA) will soon publish a notice in the Federal Register asking the public to comment on how agricultural coexistence in the United States can be strengthened.

“The Advisory Committee on Biotechnology and 21st Century Agriculture recommended that USDA support agricultural coexistence by strengthening education and outreach on this vital issue,” said Secretary Vilsack. “In response, with this notice, we are asking all those with a vested interest in coexistence to help us learn more about what coexistence means to them, how they are already contributing to it, and what more is needed to achieve coexistence. With this input, we can continue the dialogue begun by the AC21 group and find practical solutions that will help all sectors of American agriculture be successful.”

The AC21 made recommendations in five major areas regarding agricultural coexistence. In the area of education and outreach, the committee recommended that USDA foster communication and collaboration to strengthen coexistence. USDA’s notice seeks public comment to identify ways to foster communication and collaboration among those involved in all sectors of agriculture production. The comment period begins upon publication of the notice in the Federal Register and will be 60 days.

Coexistence is defined as the concurrent cultivation of crops produced through diverse agricultural systems including traditionally produced, organic, identity preserved, and genetically engineered crops. USDA supports all forms of agriculture and wants each sector to be as successful as possible providing products to markets in the United States and abroad.


AUS – THE PANIC VIRUS IS DEADLY

For GM food and vaccinations, the panic virus is a deadly disease

23 September 2013. Source: The Conversation. By Dr David Tribe and Prof Rick Roush

http://theconversation.com/for-gm-food-and-vaccinations-the-panic-virus-is-a-deadly-disease-18460

Most readers are aware of the benefits of using vaccines to boost the immune system and prevent infectious disease. Many readers will not be aware of a very different disease prevention tool: supplementing vitamins in crops through genetic modification (GM).

Anti-science opposition to both is rife; to save lives, that opposition has to stop.

The disease-prevention benefits of supplemental vitamin A were accidentally discovered in 1986 by public health scientists. They were working to improve nutrition in the villages of Aceh, Indonesia, where families are heavily dependent on rice as their main source of nutrition.

These scientists discovered that simple supplementation of infant diets with capsules containing beta-carotene (a natural source of vitamin A) reduced childhood death rates by 24%.

White rice is a very poor source of vitamin A, so the people of Aceh (like millions of poorer people in large regions of the world) suffered from vitamin A deficiency. This impaired proper development of their biological defences against infection.

We now better understand vitamin A deficiency as a disease of poverty and poor diet, responsible for near two million preventable deaths annually. It is mostly children under the age of five and women who are affected.

Many other studies carried out in several Asian, African and Latin American countries reveal the health benefits of beta-carotene supplementation in the diets of people subsisting on vitamin A-deficient staple foods.

Small wonder then that scientists internationally were outraged at the recent wanton sabotage of field trials to evaluate new varieties of rice called Golden Rice. This rice is genetically modified to contain nutritionally beneficial levels of beta-carotene.

Trenchant opposition to vaccines, and opposition to genetically modified crops, are examples of the disturbing and strong anti-scientific sentiment in many modern countries. They share some common features.

To read more http://theconversation.com/for-gm-food-and-vaccinations-the-panic-virus-is-a-deadly-disease-18460

 

 

 


AUS – HEAT GONE FROM GM DEBATE

Heat gone out of GM food debate

27 September 2013. Source: ABC Rural

www.abc.net.au/news/2013-09-27/gm-crops/4984782

 

Has the heat gone out of the genetically modified food debate?

That’s the sentiment of a science author who says people are now willing to eat GM food.

“I think the debate has been around enough that the extremes have gone out of it,” the CSIRO’s Dr Craig Cormick said.

“The hysteria has probably diminished a lot and people are no longer willing to make a gut reaction and say ‘it’s dangerous, it’s wrong, it’s against nature’.

“It’s been around for over a decade and people always go through the hot reaction at first, and then it calms down a bit and people start (thinking) ‘let’s have a discussion around this’.”

GM crops are plants that have genes removed or added to change their attributes.

In Hawaii, scientists created a GM papaya crop to overcome a deadly virus.

Cotton and canola are among the most common genetically modified Australian crops.

Dr Cormick says people are willing to eat GM foods if they understand why the crop has been modified.

He says changes in climate impact on people’s willingness to eat GM food.

“The agricultural community is talking about it seriously,” Dr Cormick said.

“We look back a couple of years during the big drought, we did find clearly in public attitudes that people were much more receptive to the idea of GM drought-resistant wheat or GM drought-resistant crops.


AUS - GM FORUM IN WA

GM Technology – The Future in Agriculture

A Free Public Event

Hosted by the Pastoralists & Graziers Association of WA (PGA)

Where: Tattersall Lecture Theatre, University of WA

When: Monday 7 October 2013

Time: 6pm

This public GM Forum is an opportunity for city-based consumers and decision-makers to further their understanding of this beneficial technology. Come and join farmers, agronomists, scientists and consumers to hear how future advances in GM technology are set to revolutionise grain growing in WA and benefit our farmers. You will hear from Australia’s leading experts in GM technology, including scientists, agronomists and farmers on why they support this safe, affordable and effective technology.

Chair: Prof Alan Robson, past Vice Chancellor of UWA

Speakers: Professor Lyn Beazley, Professor Jim Peacock, Dr John Manners, Dr Bryan Whan, Mr John Snooke, Mr Bill Crabtree

RSVP by 1 October as seats are limited.

Phone Sonya at the PGA 9479 4599 or email sonyas@pgaofwa.org.au


AUS - RADIO NATIONAL AND GM FOODS

Curse of the Frankenfoods

15 September 2013. Source: ABC Radio National

www.abc.net.au/radionational/programs/backgroundbriefing/2013-09-15/4950990#transcript

Health and safety fears have restricted the growth of genetically modified foods for decades. But is a hungry world, a new generation of consumers, and the weight of scientific evidence loosening the grip of the Frankenfoods curse? Ian Walker set aside his long standing antipathy towards GM foods to investigate.

Frankenfood. It’s the meme that keeps giving…the brainchild of an English professor from Boston named Paul Lewis, whose timing was as impeccable as his rhetorical flourish was devastating.

‘Ever since Mary Shelley’s baron rolled his improved human flesh out of the lab,’ Lewis wrote, ‘scientists have been bringing such good things to life… If they [the GMO corporations] want to sell us Frankenfood, perhaps it’s time to gather the villagers, light some torches and head to the castle.’

It was 1992 and the first GM crops were coming online for approval by America’s Food and Drug Administration.  Lewis’ turn of phrase was fabulously alliterative, catchy as a car commercial, and conjured powerful notions of something amiss.  Fish genes in tomatoes.  Nature being tampered with.  Humans playing God.  Mad scientists in their labs cackling demonically as they tinkered with the very building blocks of life.

In reality, though, scientists have been tinkering with crops since the dawn of agriculture, making them more productive, resistant to disease…shorter, fatter, bigger, better.  The development of hybrid crops in the 1930s was a game-changing moment.  Then, in the 90s, ethical, environmental and food safety concerns collided with panic about mad-cow disease to produce a backlash against the notion of crop science gone too far.  Frankenfood provided the frightening metaphor that tilted the war of words wildly in favour of the anti-GM warriors.

‘It feeds into a very deep-seated and long-held fear of technology that people have,’ explains former anti-GM activist Mark Lynas.  ‘And that’s where the Frankenstein association is so powerful.  It’s something humans are doing which they shouldn’t do.  You even get this back in Genesis with the Tree of Knowledge.  So it’s a very strong myth that goes right through human culture.’

And, while scientists weren’t exactly being burnt at the stake, some took Lewis’ rallying cry to heart and found righteous cause to destroy important scientific experiments in the trial crop stages. Lynas excelled in this for nearly two decades, leading campaigns in the UK and Europe.

‘It was my life,’ he says. ‘We did all of these kinds of night-time actions against GM crops, going and chopping them down. We thought we were decontaminating the landscape. We thought what we were doing was environmentally responsible and important.’

What he didn’t realise at the time, Lynas says now, was that the real Frankenstein’s monster was not GM technology, but the reaction against it by people like him and his anti-GM cohorts.  Back in January 2013, his public apology to the Oxford Farming Conference for what he now describes as his ‘years of wrongheadedness’ made headlines around the world.  At the time, it was nerve-wracking and heartfelt.

‘I’d kind of had enough, and I just wanted to put all of my cards on the table and speak from the heart, really, and say, “I got this wrong”. I think everyone else in the anti-GM movement has got this wrong. We need to take stock of where we are and I for one am issuing an apology.’

Oxford was a fitting place for such a dramatic change of heart, being the same venue where Lynas had earned notoriety for throwing a cream pie in the face of Bjorn Lomborg, an outspoken critic of eco-apocalyptic agendas.  ‘Pies for lies,’ yelled Lynas as his underarm lob hit its target.

This time, he was asking for forgiveness from a gathering of farmers and scientists, soberly recanting ‘demonizing an important technological option which can be used to benefit the environment…I could not have chosen a more counter-productive path.’  No-one preaches better than a convert.

Lynas is a respected environmentalist, and a strong campaigner on climate change who’s written award-winning books. What irked him was the slow realisation that his passionately held views on GM were inconsistent with his reliance on evidence-based science when arguing his position on human-induced climate change.  When it came to GM, he admits, he actively ignored the weight of evidence in favour of biotechnology.

The argument he puts is that an estimated three trillion meals containing food derived from GM-bred plants have been eaten in 29 countries over 15 years without one single substantiated case of harm. ‘You are more likely,’ he quips, ‘to get hit by an asteroid than to get hurt by GM food.’

Mark Lynas was a big fish in the anti-GM pond.  Within days of his conference appearance, the video of his speech went viral.  There are now versions in more than a dozen languages, translated by volunteers in different countries around the globe.

The Lynas conversion was a revelation for journalist Jon Entine, who wrote up the story for Forbes magazine. Entine saw it as the potential dynamite it was for the ongoing GM debate. But, he says, it also pointed to a turning point in our thinking about the interface between technology and the natural world.

‘Every once in a while our society faces major inflection points when certain technologies come into play,’ Entine explains. ‘We saw it in the 1800s with the railroad, we’ve seen it with nuclear technology, we’ve seen it with computer technology. And I really think that we’re in this kind of inflection period with biotechnology.’

‘It is literally changing the way we can think about nature.  And I mean in a good sense. I don’t believe we’re violating God’s way, or any kind of natural order of things, but it is a profound experience, which is why it’s scary to many people.’

As Entine pointed out in his article, Lynas took a somewhat slow-road to Damascus. It happened over a number of years of realising that, while he was backing the claims in his various books about climate change with scientific evidence, he was doing the opposite when it came to GM.  He actively ignored the weight of the evidence in favour.  Finally, Lynas says, he had to admit his own cherished beliefs about GM turned out to be little more than ‘green urban myths’.

‘There were so many myths,’ he recounts. ‘Probably first off was this idea that somehow there’s a unique property that genes have when they belong in different species, so that there’s something carroty about carrot genes or fishy about fish genes. So I don’t think I realised that DNA is this universal code, and it’s just a number…you know, four sequences of letters, basically, is how we interpret it, and you can chop and change it between different species with actually very little impact.’

As a new convert, Lynas has joined the likes of Jon Entine, as a champion of the potential benefits of biotechnology.  His conversion has coincided, or highlighted, a new urgency to feed a hungry world, a new generation of consumers, more scrutiny of anti-GM activism, plus the weight of scientific evidence showing it is safe.

Lynas makes the case strongly that it’s time for scientists to speak out about the benefits of biotechnology.  For too long, he says, they’ve been cowed by the strident fear campaigns around Frankenfood.  And, it seems, some are fighting back and talking up a new phase of the technology.  Like Australia’s Professor James Dale.

‘We’re just starting to see the revolution,’ says Dale, the Director of the QUT’s Centre for Tropical Crops and Biocommodities.  ‘Virtually all of the really big crop genomes have been sequenced, we’re now starting to identify what genes in those genomes are going to be really useful.’

The prospects and potential of what’s to come has been dubbed ‘Biotech Version 2.0’.  And, Dale is convinced, it’s likely to further sway the debate.

‘A lot of it is going to be targetted towards the things that we’re really concerned about, with climate change, with drought, with flooding, submersion. So we’re starting to see those traits coming through and the next generation of GM crops are going to be of much greater benefit to humanity than round one.’

Dale’s Banana 21 Project is a case in point. It’s funded by the Gates Foundation and is tackling Vitamin A deficiency in some of the poorest parts of Africa by enriching a staple food—in this case, bananas for Uganda—via GM. 

It might help save the 670-thousand or so kids who die from micronutrient malnutrition every year, and half as many again who go blind.  These genetically-modified ‘golden bananas’ have been developed in Australia and Professor Dale claims the results so far are very promising.

‘We have provitamin A Cavendish bananas with double our target level of provitamin A, so that’s fabulous. We now know which genes to use and which promoters to use. We transferred that technology to Uganda, and they now have their bananas in the field. Just very recently they identified a line which also has double the target level of provitamin A.  It’s really exciting, so we’re now moving into development phase.’

The project’s on track to produce enriched bananas ready for human eating trials by next year.  But not if some of the NGOs in Uganda have their way.  Lynas has just returned from a visit there with some hair-raising tales of treachery by anti GM activists.

He says he’s heard stories from local MPs who have had activists going into their Muslim constituencies telling people that the scientists are putting pig genes into bananas—the bio-fortified and the bacteria-resistant bananas—which you wouldn’t be allowed to eat as a Muslim.

‘Literally, people have been going crazy about this,’ Lynas reports.  ‘There’s almost been violence breaking out. So, the anti-GM activists have stooped so low as to cause religious violence in order to stop this technology.’


AUS – GM BANANA RESEARCH

GM bananas: from nutrition to disease resistance

Source: www.freshfruitportal.com/2013/08/23/gm-bananas-from-nutrition-to-disease-resistance/?country=others

This article outlines biotechnology research underway involving bananas (vitamin enhanced and disease resistant) led by Professor James Dale at the Queensland University of Technology (QUT).

Professor James Dale and his team at the Queensland University of Technology (QUT) have come far since gaining support from the Bill and Melinda Gates Foundation (BMGF) in 2005. Initially focused on vitamin-rich genetically modified (GM) bananas for growers in Uganda, work has extended to India with disease resistance thrown into the mix, while Dale mentions the possibility of collaboration with Nigerian and Indonesian scientists in the future. Catching up with him in Brisbane, www.freshfruitportal.com hears why transgenic bananas may face less resistance than other GMO crops, and their potential if consumers accept the technology.

…“In the early 1990s we decided we were going to get involved in genetic modification. I should say that was before anybody said that it was a naughty thing to do – we thought, ‘wow, what a fabulous opportunity to actually improve bananas’, and there’s a huge number of vegetatively propagated crops which you can’t breed from the already accepted cultivars.

This fact has likely been instrumental for the establishment of QUT’s GM field trials south of Innisfail in North Queensland; the heart of Australia’s banana-growing district.

“We invited any of the banana growers who wanted to come before we planted the field trial, and we went through everything. It took a couple of hours, and they were really comfortable with what we’re doing,” he says.

“There’s no threat because there’s no transgene flow.”

Disease resistance

Dale says his team of 15 people is still working on resistance to Bunchy Top but hasn’t “quite got there yet”, and has also developed a way of controlling Panama Race I – which wiped out previous staple banana variety Gros Michel – through stress tolerant genes.

“For the original genes we’d put in, the best one was from a nematode and that gave us a hint of what we should do, and then we went and looked for the plant equivalents and we’ve been able to use those.

“That’s one strategy. Another is we’ve gone to a wild diploid banana called musa acuminata [spp.] malaccensis which grows in Indonesia and Malaysia. Some of those plants are absolutely immune to Tropical Race IV.

“There are about 25,000 types of genes, so it’s needle in a haystack type of stuff. So we’ve got to identify the right gene; we haven’t got the results from the field trial in the Northern Territory yet.

“Because it’s a slow-forming disease, we’d want to have the results probably by the end of next year. We’d be confident if we had lines there that are still standing up, and none of them are diseased, that there’s real resistance there.”

He adds that this variety is also resistant to Black Sigatoka, but his team is not working on that fungus.

“We know that malaccensis is also resistant to Black Sigatoka, so that will come. And it would be interesting to see how some of the big banana companies cope with that, when they’d say, ‘gee, we wouldn’t have to spray if we had these GM bananas’.”

Nutrition for the developing world

Dale’s work received a boost in 2004 when the BMGF put out a call for expressions of interest around grand challenges in global health.

“Most of those global challenges were new vaccines, antibiotics and the control of insect vectors of human diseases; there was one grant challenge nine, which was to develop staple crops with a complete set of micronutrients.

“We’d already started to work with the National Agricultural Research Organization in Uganda so I suggested we make an expression of interest.

“In Uganda their staple food is bananas, and in that whole region there’s very high banana consumption, very high levels of Vitamin A deficiency, and very high levels of iron deficiency; anemia.”

QUT received the funding to collaborate with their Ugandan counterparts, and Dale says “remarkable” progress has been made since then.

“So we’ve now got bananas with more than double our target levels that we wanted for provitamin A.”

He says bananas already have vitamin A through beta-carotene and alpha-carotene, but genetic modification has allowed the scientists to augment the level.

“We were able to take the genes from one of them [beta-carotene] that makes very large amounts and put that banana gene into East African Highland Bananas and into Cavendish.

“The whole issue of vitamin deficiency is really complex – micronutrient deficiencies particularly. There is still this very poor population that don’t buy food and don’t access health clinics, and that can be anywhere between 30-50% of the population in developing countries.

The first field trial for Vitamin A was in 2009, with a plan of developing the technology in Australia and then transferring that technology but not the plants to Uganda.

“Now that project is moving into the development phase where we can go and develop an elite line that we’ll take all the way through to farmer release in Uganda, and that will be available to other countries in the region if they want it.

He adds the next part of the Ugandan project is to increase iron levels, which is “much harder”.

“But we’re getting there. We’ve got a 50% increase but we actually want a 400% increase. We’ve got our next field trial in Australia already happening.”

On the back of the Ugandan collaboration’s success, QUT was approached by the Indian government to work on a similar project with its Department of Biotechnology.

“They wanted disease resistance as well, which we put in – they want resistance to bunchy top and Panama wilt.”

 


INT – STEM RUST RESISTANCE GENE DISCOVERY

19 August 2013. Source: University of California, Davis

http://news.ucdavis.edu/search/news_detail.lasso?id=10655.

A new gene that will equip wheat plants to resist the deadly stem rust disease has been discovered by an international team that includes plant scientists from Australia, United States, and China

The research team, which included co-author Jan Dvorak, a professor and wheat geneticist at UC Davis, succeeded in cloning the Sr33 gene, known to exist in Aegilops tauschii, a wild relative of common bread wheat.

“We are hopeful that the Sr33 gene and the Sr35 gene, which our colleagues at UC Davis helped to isolate, can be ‘pyramided,’ or combined, to develop wheat varieties with robust and lasting resistance to wheat stem rust disease,” Dvorak said.

The discovery of genes that confer resistance to wheat stem rust disease is vitally important for global food security, as a new, highly aggressive race of the fungus that causes wheat stem rust appeared about a decade ago in Africa and has been spreading from there. That new UG99 race, which causes rust-colored bumps to form on the stems and leaves of the wheat plants, threatens global wheat grain production.

Identification and cloning of resistance genes is expected to enable plant breeders to use traditional breeding techniques to develop new wheat varieties that will be resistant to the new strain of wheat stem rust disease, before it grows into a global pandemic.

Lead author on this study was Evans Lagudah from CSIRO Plant Industry.


PHILIPPINES – GOLDEN RICE TRIAL VANDALISED

Malnutrition fight not over, Golden Rice research continues

8 August 2013. Source: International Rice Research Institute (IRRI), media release.

http://irri.org/index.php?option=com_k2&view=item&id=12638:malnutrition-fight-not-over-golden-rice-research-continues&lang=en

The International Rice Research Institute (IRRI) and the Department of Agriculture (DA) – Philippine Rice Research Institute (PhilRice) are continuing to fight malnutrition in the Philippines, and continuing Golden Rice research as a potential way to reduce vitamin A deficiency.

“Golden Rice field trials are part of our work to see if Golden Rice can be a safe and effective way to reduce vitamin A deficiency in the Philippines – to reduce malnutrition,” said Dr Bruce Tolentino, deputy director general of communications and partnerships at IRRI.

“Vitamin A deficiency is “horrible and unnecessary, and we want to do our part to help to reduce it.”

“Our Golden Rice research is part of our humanitarian work to reduce vitamin A deficiency that mostly affects women and children – causing sickness, blindness, and even death,” Tolentino said. “Earlier today one of our Golden Rice field trials located in the Bicol region of the Philippines was vandalized. We are really disappointed that our Golden Rice field trial was vandalized, but it is just one trial and we will continue our Golden Rice research to improve human nutrition.”

In the Philippines, vitamin A deficiency affects approximately 1.7 million children (15.2%) aged 6 months to 5 years. Subclinical vitamin A deficiency affects one out of every ten pregnant women.

Golden Rice is a new type of rice that contains beta carotene, which is converted to vitamin A when eaten. Research so far indicates that eating about one cup a day of Golden Rice could provide half of an adult’s vitamin A needs.

IRRI is working with leading nutrition and agricultural research organisations to develop and evaluate Golden Rice as a potential new way to reduce vitamin A deficiency in the Philippines, Bangladesh and other countries.

In the Philippines, all GM research and development under contained conditions are overseen by the Department of Science and Technology – National Committee on Biosafety of the Philippines. The Department of Agriculture’s Bureau of Plant Industry (DA-BPI) strictly monitors field trials, coordinates evaluation of biosafety information, and approves GM crops if appropriate.

Golden Rice field trials are being conducted in the Philippines by PhilRice and IRRI. The field trials have been permitted by DA-BPI, the national regulatory authority in the Philippines for crop biotechnology research and development, after establishing that the trials will pose no significant risks to human health and environment.

The Golden Rice field site that was vandalized was located within the Department of Agriculture Regional Field Unit 5’s (DA-RFU5) Bicol Experiment Station in Pili, Camarines Sur. The Golden Rice trial site is less than 1,000 square metres (or 0.1 hectare). Nearly all plants have been uprooted and left on site.

“We all want to answer questions about Golden Rice,” Tolentino added. “Therefore, we need to test Golden Rice and test it according to the best and most rigorous research standards. This means continuing field trials to ensure there is adequate data and analysis that will enable informed decisions on Golden Rice.”

“At IRRI, we remain dedicated to improving nutrition for everyone in the Philippines and in other rice-eating countries,” Tolentino said.

“We’re here for the long term, and Golden Rice and other healthier rice are part of our efforts to help reduce malnutrition amongst rice-consumers.